An Open-Source Research Model for Creating a Cost-effective Intervention for the Treatment of Amblyopia

An Open-Source Research Model for Creating a Cost-effective Intervention for the Treatment of Amblyopia

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Créer le: octobre 18, 2011
Dernière mise à jour

Stade de l'Innov'Action
1. Idée
2. Start-up
3. Evolution
4. Mise en oeuvre
5. Portée

This project could become the first open-source research project in medical research history.
The central concept of the model includes “opening the source” of an idea or method and sharing the resources of it before it is tested or after initial testing, and making it available for researchers and enthusiasts worldwide to improve, adopt, test, and use. This model allows for research projects with low costs and rapid unbiased dissemination of information and evidence regarding the outcomes of a certain intervention.
The presented system consists of a pair of glasses with two color filters and software for use on a personal computer. The software is designed such that some active graphic components can only be seen by the amblyopic eye and are filtered-out for the other eye. Some components would be seen by both to encourage fusion. In result, the patient must use both eyes and specifically the amblyopic eye to play the games. Games will be shared throughout the community for all persons interested to use, glasses can be produced locally.

Problem

This project could become the first open-source research project in medical research history. The central concept of the model includes “opening the source” of an idea or method and sharing the resources of it before it is tested or after initial testing, and making it available for researchers and enthusiasts worldwide to improve, adopt, test, and use. This model allows for research projects with low costs and rapid unbiased dissemination of information and evidence regarding the outcomes of a certain intervention. The presented system consists of a pair of glasses with two color filters and software for use on a personal computer. The software is designed such that some active graphic components can only be seen by the amblyopic eye and are filtered-out for the other eye. Some components would be seen by both to encourage fusion. In result, the patient must use both eyes and specifically the amblyopic eye to play the games. Games will be shared throughout the community for all persons interested to use, glasses can be produced locally.

Solution

Open source research has never been done before in this sense. This study will provide an environment where researchers worldwide can collaborate and participate in, contribute to, and use the study platform and materials. In addition, the intervention is also novel. Virtual reality (VR)-based treatment has been introduced as a potential option for amblyopia management, presumably without involving the problems of occlusion and penalization, including variable and unsatisfactory outcomes, long duration of treatment, poor compliance, psychological impact, and complications. However, VR-based treatment is costly and not accessible for most children. Our proposed intervention introduces a method that encompasses the advantages of VR-based treatment at a lower cost.

Exemple

The main activity includes introducing the first open source research project, via a project website as a model for future open source research projects. The project will consist of basically disclosing the main ideas, processes, and utilities of the project, prior to testing and publication, and encouraging other researchers worldwide to use these resources and add to them (engaging volunteer work and lowering costs), while testing them simultaneously (decreasing the bias brought about by having the manufacturer or patent holder test and publish first).

Marché

This study will immediately influence the researchers and academic healthcare workers globally. Subsequently, physicians and practitioners can use the results. Ultimately, the faster dissemination of science and lower cost to obtain working therapies, will have its impact on the patients and the general population, and lower costs could mean a higher effect on low-income populations.

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All financial help is completely welcome, it would help the project grow!

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Suivi de l'Evolution

Stage: Milestone 1 of 4
Start
10/18/11
End
Milestone
Date of Completion 10/19/11
Milestone
Connect
Date of Completion 11/05/11
In Progress
Reaching out to 300 potential and interested collaborators worldwide
In Progress
Receiving feedback from at least 30 collaborators worldwide
In Progress
Start collaborations with at least 3 parties
Milestone
Pilot
Date of Completion 11/30/11
In Progress
Manufacture filter glasses locally in 1 locale
In Progress
Test in 6 children
In Progress
Generate report
In Progress
Fix gliches
Achievement
Connecté! sur
Date 11/30/11
Milestone
Expand
Date of Completion 06/20/12
In Progress
Find web space
In Progress
Launch open-source research project website
In Progress
Host at least 3 projects
Milestone 1
Connect
Notre Rapport d'Impact:
Ali Rastegarpour hasn't posted any impact reports yet.

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Commentaires & Activités

Commentaires

Alyssa Feldmann profile img
mar, 29/11/2011 - 13:46

Ali,

Thank you for supporting the Beta testing period of Changeshop. From the looks of your Growth Tracker, it seems that you've thought through the immediate steps to scaling your project. We're interested in what happens after the pilot milestone. What does expansion look like? What are the longer-term goals after expansion and what will you need to get there? We're hoping that the Growth Tracker will provide a comprehensive view of your organization's current and future growth. We look forward to seeing Impact Reports on your accomplishments!

All the best,
Alyssa Feldmann and Jessi Wolz